Browse free open source Python Frameworks and projects below. Use the toggles on the left to filter open source Python Frameworks by OS, license, language, programming language, and project status.

  • Quality and compliance software for growing life science companies Icon
    Quality and compliance software for growing life science companies

    Unite quality management, product lifecycle, and compliance intelligence to stay continuously audit-ready and accelerate market entry

    Automate gap analysis across FDA, ISO 13485, MDR, and 28+ regulatory standards. Cross-map evidence once, reuse across submissions. Get real-time risk alerts and board-ready dashboards, so you can expand into new markets with confidence
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  • Manage your hosting business with our vacation rental software Icon
    Manage your hosting business with our vacation rental software

    Empowering your short-term rental business to succeed

    Whether you’re a new or established business, you can rely on Lodgify’s vacation rental property management software for support through every step of your journey.
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  • 1
    Bottle

    Bottle

    bottle.py is a fast and simple micro-framework for python applications

    Bottle is a minimalist web framework for building small web applications and APIs in Python. It is distributed as a single file with no external dependencies, making it perfect for rapid development, prototyping, or embedded use. Despite its small size, Bottle supports routing, templates, request handling, and plugin support, offering a full-featured toolkit in an extremely compact package.
    Downloads: 4 This Week
    Last Update:
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  • 2
    Connexion

    Connexion

    Swagger/OpenAPI First framework for Python on top of Flask

    Connexion is a framework on top of Flask that automagically handles HTTP requests defined using OpenAPI (formerly known as Swagger), supporting both v2.0 and v3.0 of the specification. Connexion allows you to write these specifications, then maps the endpoints to your Python functions. This is what makes it unique from other tools that generate the specification based on your Python code. You are free to describe your REST API with as much detail as you want and then Connexion guarantees that it will work as you specified. We built Connexion this way in order to simplify the development process. Reduce misinterpretation about what an API is going to look like. With Connexion, you write the spec first. Connexion then calls your Python code, handling the mapping from the specification to the code. This incentivizes you to write the specification so that all of your developers can understand what your API does, even before you write a single line of code.
    Downloads: 4 This Week
    Last Update:
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  • 3
    Django Celery

    Django Celery

    Old Celery integration project for Django

    Celery is a simple, flexible, and reliable distributed system to process vast amounts of messages, while providing operations with the tools required to maintain such a system. It’s a task queue with focus on real-time processing, while also supporting task scheduling. Celery has a large and diverse community of users and contributors, you should come join us on IRC or our mailing-list. Celery is Open Source and licensed under the BSD License. A task queue’s input is a unit of work called a task. Dedicated worker processes constantly monitor task queues for new work to perform. Celery communicates via messages, usually using a broker to mediate between clients and workers. To initiate a task the client adds a message to the queue, the broker then delivers that message to a worker. Celery requires a message transport to send and receive messages.
    Downloads: 4 This Week
    Last Update:
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  • 4
    Django Two-Factor Authentication

    Django Two-Factor Authentication

    Complete Two-Factor Authentication for Django

    Complete Two-Factor Authentication for Django. Built on top of the one-time password framework django-otp and Django's built-in authentication framework django.contrib.auth for providing the easiest integration into most Django projects. Inspired by the user experience of Google's Two-Step Authentication, allowing users to authenticate through call, text messages (SMS), by using a token generator app like Google Authenticator or a YubiKey hardware token generator (optional). If you run into problems, please file an issue on GitHub, or contribute to the project by forking the repository and sending some pull requests. The package is translated into English, Dutch and other languages. Please contribute your own language using Transifex. Test drive this app through the example app. It demos most features except the Twilio integration. The example also includes django-user-sessions for providing Django sessions with a foreign key to the user.
    Downloads: 4 This Week
    Last Update:
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  • Professional Email Hosting for Small Business | Greatmail Icon
    Professional Email Hosting for Small Business | Greatmail

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  • 5
    Invenio

    Invenio

    Invenio digital library framework

    Invenio is a highly customizable open-source framework for building large-scale digital repositories and research data platforms. Developed by CERN, it is designed to manage, index, and provide access to metadata-rich content such as publications, datasets, and multimedia files. Invenio provides a modular architecture, making it suitable for libraries, archives, and research institutions.
    Downloads: 4 This Week
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  • 6
    Kubernetes Operator Pythonic Framework

    Kubernetes Operator Pythonic Framework

    A Python framework to write Kubernetes operators in just a few lines

    Kopf —Kubernetes Operator Pythonic Framework— is a framework and a library to make Kubernetes operator's development easier, just in a few lines of Python code. The main goal is to bring the Domain-Driven Design to the infrastructure level, with Kubernetes being an orchestrator/database of the domain objects (custom resources), and the operators containing the domain logic (with no or minimal infrastructure logic). The project was originally started as zalando-incubator/kopf in March 2019, and then forked as nolar/kopf in August 2020: but it is the same codebase, the same packages, the same developer(s). A full-featured operator in just 2 files: a Dockerfile + a Python file (*). Handling functions registered via decorators with a declarative approach. No infrastructure boilerplate code with K8s API communication. Both sync and async handlers, with sync ones being threaded under the hood. Detailed documentation with examples.
    Downloads: 4 This Week
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  • 7
    Piccolo

    Piccolo

    A fast, user friendly ORM and query builder which supports asyncio

    Piccolo is a modern, fast, and type-safe ORM for Python, designed with developer ergonomics in mind. It provides a clean syntax for defining schemas and building queries while supporting both sync and async execution. With built-in admin tools and rich introspection, Piccolo is suitable for web apps, APIs, and small-to-medium scale backends that prioritize clarity and speed.
    Downloads: 4 This Week
    Last Update:
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  • 8
    PyObjC

    PyObjC

    The Python <-> Objective-C Bridge with bindings for macOS frameworks

    PyObjC is a Python-Objective-C bridge that allows Python scripts to interact with macOS Cocoa libraries. It enables developers to write native macOS apps entirely in Python by accessing Objective-C APIs.
    Downloads: 4 This Week
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  • 9
    RAG Anything

    RAG Anything

    RAG-Anything: All-in-One RAG Framework

    RAG-Anything is an open-source unified framework that extends the Retrieval-Augmented Generation (RAG) paradigm to fully multimodal document and knowledge retrieval, enabling systems to ingest, parse, represent, and query rich content that includes text, images, tables, formulas, and other structured or visual elements. Traditional RAG systems are typically limited to text and cannot effectively work across heterogeneous document layouts, but RAG-Anything addresses this by modeling multimodal content in ways that preserve cross-modal relationships and semantic context, often treating content elements as interconnected knowledge entities rather than separate data silos. The system uses a multi-stage pipeline (e.g., document parsing, content analysis, knowledge graph construction, intelligent retrieval) so queries can navigate across modalities with deeper understanding and relevance.
    Downloads: 4 This Week
    Last Update:
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  • Instant Remote Support Software. Unattended Remote Access Software. Icon
    Instant Remote Support Software. Unattended Remote Access Software.

    Zoho Assist, your all-in-one remote access solution, helps you to access and manage remote devices.

    Zoho Assist is cloud-based remote support and remote access software that helps you support customers from a distance through web-based, on-demand remote support sessions. Set up unattended remote access and manage remote PCs, laptops, mobile devices, and servers effortlessly. A few seconds is all you need to establish secure connections to offer your customers remote support solutions.
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  • 10
    Ray

    Ray

    A unified framework for scalable computing

    Modern workloads like deep learning and hyperparameter tuning are compute-intensive and require distributed or parallel execution. Ray makes it effortless to parallelize single machine code — go from a single CPU to multi-core, multi-GPU or multi-node with minimal code changes. Accelerate your PyTorch and Tensorflow workload with a more resource-efficient and flexible distributed execution framework powered by Ray. Accelerate your hyperparameter search workloads with Ray Tune. Find the best model and reduce training costs by using the latest optimization algorithms. Deploy your machine learning models at scale with Ray Serve, a Python-first and framework agnostic model serving framework. Scale reinforcement learning (RL) with RLlib, a framework-agnostic RL library that ships with 30+ cutting-edge RL algorithms including A3C, DQN, and PPO. Easily build out scalable, distributed systems in Python with simple and composable primitives in Ray Core.
    Downloads: 4 This Week
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  • 11
    Reflex Dev

    Reflex Dev

    Web apps in pure Python

    Reflex is a Python framework for building full-stack web apps entirely in Python—without writing JavaScript for the frontend. It provides fast live reloads, built-in state management, deployment tooling, and optional AI-powered scaffolding to accelerate development.
    Downloads: 4 This Week
    Last Update:
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  • 12
    Unicorn

    Unicorn

    The magical reactive component framework for Django

    Quickly add in simple interactions to regular Django templates without learning a new templating language. Stop fighting with a new JavaScript build tool and separate process to use yet another frontend framework. Building a feature-rich API is complicated. Skip creating a bunch of serializers and just use Django. Unicorn progressively enhances a normal Django view, so the initial render of components is fast and great for SEO. The end result is that you can focus on writing regular Django templates and Python classes without needing to switch to another language or build unnecessary plumbing. Best of all, the JavaScript portion is a paltry. Unicorn is a reactive component framework that progressively enhances a normal Django view, makes AJAX calls in the background, and dynamically updates the DOM. It seamlessly extends Django past its server-side framework roots without giving up all of its niceties or re-building your website.
    Downloads: 4 This Week
    Last Update:
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  • 13
    web2py

    web2py

    Free and open source full-stack enterprise framework

    Free open source full-stack framework for rapid development of fast, scalable, secure and portable database-driven web-based applications. Written and programmable in Python (version 3 and 2.7). Everything you need in one package including fast multi-threaded web server, SQL database and web-based interface. No third-party dependencies but works with third-party tools. Create, modify, deploy and manage applications from anywhere using your browser. One web2py instance can run multiple web sites using different databases. Try the interactive demo. Start with some quick examples, then read the manual and the Sphinx docs, watch videos, and join a user group for discussion. Take advantage of the layouts, plugins, appliances, and recipes.
    Downloads: 4 This Week
    Last Update:
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  • 14
    SIGAR (System Information Gatherer and Reporter) is a cross-platform, cross-language library and command-line tool for accessing operating system and hardware level information in Java, Perl and .NET.
    Downloads: 33 This Week
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  • 15
    Blankly

    Blankly

    Easily build, backtest and deploy your algo in just a few lines

    ​Blankly is a live trading engine, backtest runner and development framework wrapped into one powerful open-source package. Models can be instantly backtested, paper traded, sandbox tested and run live by simply changing a single line. We built blankly for every type of quant including training & running ML models in the same environment, cross-exchange/cross-symbol arbitrage, and even long/short positions on stocks (all with built-in WebSockets). Blankly is the first framework to enable developers to backtest, paper trade, and go live across exchanges without modifying a single line of trading logic on stocks, crypto, and forex. Every model needs to figure out how to buy and sell. We make it super easy for you so you can focus on building better trading algos. Your models can run on any platform, and on any supported exchange. We make that as easy as just changing one line of code.
    Downloads: 3 This Week
    Last Update:
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  • 16
    Database-backed Periodic Tasks

    Database-backed Periodic Tasks

    Celery Periodic Tasks backed by the Django ORM

    This extension enables you to store the periodic task schedule in the database. The periodic tasks can be managed from the Django Admin interface, where you can create, edit and delete periodic tasks and how often they should run. Usage and installation instructions for this extension are available from the Celery documentation. If you change the Django TIME_ZONE setting your periodic task schedule will still be based on the old timezone. To create a periodic task executing at an interval you must first create the interval object. If you have multiple periodic tasks executing every 10 seconds, then they should all point to the same schedule object.
    Downloads: 3 This Week
    Last Update:
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  • 17
    Django Lifecycle Hooks

    Django Lifecycle Hooks

    Declarative model lifecycle hooks, an alternative to Signals

    This project provides a @hook decorator as well as a base model and mixin to add lifecycle hooks to your Django models. Django's built-in approach to offering lifecycle hooks is Signals. However, my team often finds that Signals introduce unnecessary indirection and are at odds with Django's "fat models" approach. Django Lifecycle Hooks supports Python 3.7, 3.8 and 3.9, Django 2.0.x, 2.1.x, 2.2.x, 3.0.x, 3.1.x, and 3.2.x. For simple cases, you might always want something to happen at a certain point, such as after saving or before deleting a model instance. When a user is first created, you could process a thumbnail image in the background and send the user an email.
    Downloads: 3 This Week
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  • 18
    Flask-JWT-Extended

    Flask-JWT-Extended

    An open source Flask extension that provides JWT support

    Flask-JWT-Extended not only adds support for using JSON Web Tokens (JWT) to Flask for protecting routes, but also many helpful (and optional) features built in to make working with JSON Web Tokens easier. Adding custom claims to JSON Web Tokens. Automatic user loading (current_user). Custom claims validation on received tokens. Refresh tokens, first-class support for fresh tokens for making sensitive changes. Token revoking/blocklisting. Storing tokens in cookies and CSRF protection. Adding custom claims to JSON Web Tokens. Automatic user loading (current_user). Custom claims validation on received tokens. Refresh tokens. First-class support for fresh tokens for making sensitive changes. Token revoking/blocklisting. Storing tokens in cookies and CSRF protection.
    Downloads: 3 This Week
    Last Update:
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  • 19
    Flask-MongoEngine

    Flask-MongoEngine

    MongoEngine flask extension with WTF model forms support

    Flask-MongoEngine is a Flask extension that provides integration with MongoEngine, WtfForms and FlaskDebugToolbar. By default, Flask-MongoEngine will install integration only between Flask and MongoEngine. Integration with WTFForms and FlaskDebugToolbar are optional and should be selected as extra option, if required. This is done by users request, to limit amount of external dependencies in different production setup environments. All methods end extras described below are compatible between each other and can be used together. We still maintain special case for Flask = 1.1.4 support (the latest version in 1.x.x branch). To install flask-mongoengine with required dependencies use legacy extra option. Flask-mongoengine can be installed with Flask-WTF and WTFForms support. This will extend project dependencies with Flask-WTF, WTFForms and related packages.
    Downloads: 3 This Week
    Last Update:
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  • 20
    Misago

    Misago

    Misago is fully featured modern forum application

    Misago aims to be a complete, featured and modern forum solution that has no fear to say 'NO' to common and outdated opinions about how forum software should be made and what it should do. Your users may register accounts, set avatars, change options and edit their profiles. They have the option to reset forgotten passwords. Site admins may require users to confirm validity of their e-mail addresses via e-mail sent activation link, or limit user account activation to administrator action. They can use custom Q&A challenge, ReCAPTCHA, Stop Forum Spam or IP's blacklist to combat spam registrations. Pletora of settings are available to control user account behavior, like username lengths or avatar restrictions. Presence features let site members know when other users are online, offline or banned. Individual users have setting to hide their activity from non-admins.
    Downloads: 3 This Week
    Last Update:
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  • 21
    Nextcord

    Nextcord

    A Python wrapper for the Discord API forked from discord.py

    A modern, easy-to-use, feature-rich, and async-ready API wrapper for Discord written in Python.
    Downloads: 3 This Week
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  • 22
    Optuna

    Optuna

    A hyperparameter optimization framework

    Optuna is an automatic hyperparameter optimization software framework, particularly designed for machine learning. It features an imperative, define-by-run style user API. Thanks to our define-by-run API, the code written with Optuna enjoys high modularity, and the user of Optuna can dynamically construct the search spaces for the hyperparameters. Optuna Dashboard is a real-time web dashboard for Optuna. You can check the optimization history, hyperparameter importances, etc. in graphs and tables. You don't need to create a Python script to call Optuna's visualization functions. Automated search for optimal hyperparameters using Python conditionals, loops, and syntax. Efficiently search large spaces and prune unpromising trials for faster results. Parallelize hyperparameter searches over multiple threads or processes without modifying code.
    Downloads: 3 This Week
    Last Update:
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  • 23
    Pyrogram

    Pyrogram

    Elegant, modern and asynchronous Telegram MTProto API framework

    Pyrogram is a modern, elegant and asynchronous MTProto API framework. It enables you to easily interact with the main Telegram API through a user account (custom client) or a bot identity (bot API alternative) using Python. Ready: Install Pyrogram with pip and start building your applications right away. Easy: Makes the Telegram API simple and intuitive, while still allowing advanced usages. Elegant: Low-level details are abstracted and re-presented in a more convenient way. Fast: Boosted up by TgCrypto, a high-performance cryptography library written in C. Type-hinted: Types and methods are all type-hinted, enabling excellent editor support. Async: Fully asynchronous (also usable synchronously if wanted, for convenience). Powerful: Full access to Telegram's API to execute any official client action and more.
    Downloads: 3 This Week
    Last Update:
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  • 24
    Status - a Mobile Ethereum OS

    Status - a Mobile Ethereum OS

    A free (libre) open source, mobile OS for Ethereum

    Status is a secure messaging app, crypto wallet, and Web3 browser built with state-of-the-art technology. Integrated into one powerful super app for private secure communication. Safely send, store and receive cryptocurrencies including ERC20 and ERC721 tokens with the Status crypto wallet. Only you hold the keys to your funds. Status' intuitive design protects you and your funds from attacks. Status uses an open-source, peer-to-peer protocol, and end-to-end encryption to protect your messages from third parties. Keep your private messages private with Status. Browse the growing ecosystem of DApps including marketplaces, exchanges, games, and social networks. The latest security standards ensure a private browsing experience. You will never be asked for a phone number, email address, or bank account when generating a Status account. Stay private and selectively reveal yourself to the world with Status.
    Downloads: 3 This Week
    Last Update:
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  • 25
    Superduper

    Superduper

    Superduper: Integrate AI models and machine learning workflows

    Superduper is a Python-based framework for building end-2-end AI-data workflows and applications on your own data, integrating with major databases. It supports the latest technologies and techniques, including LLMs, vector-search, RAG, and multimodality as well as classical AI and ML paradigms. Developers may leverage Superduper by building compositional and declarative objects that out-source the details of deployment, orchestration versioning, and more to the Superduper engine. This allows developers to completely avoid implementing MLOps, ETL pipelines, model deployment, data migration, and synchronization. Using Superduper is simply "CAPE": Connect to your data, apply arbitrary AI to that data, package and reuse the application on arbitrary data, and execute AI-database queries and predictions on the resulting AI outputs and data.
    Downloads: 3 This Week
    Last Update:
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