Open Source C# Bio-Informatics Software

ProteoWizard development moved to GitHub in 2018. The ProteoWizard Library is a set of software libraries and tools for rapid development of proteomics data analysis software. The libraries are cross-platform and built from the ground up using modern C++ techniques.

OpenVista(R) is the open-source version of VistA, an enterprise grade health care information system developed by the U.S. Veterans Affairs and deployed at 1,500 global facilities. OpenVista is a registered trademark of Medsphere Systems Corporation

!!! New website is https://unity.mol3d.tech and new releases/source code are now on Github : https://github.com/LBT-CNRS/UnityMol-Releases !!!! Implementation of a visualization prototype for molecular structures and networks using the Unity3D game engine. Implementation of numerous graphical methods as spheres, particle systems, bond, etc.. as well as our recent HyperBalls methodology (see: www.hyperballs.sf.net).

Open source code base for enabling software innovation in imaging. The extensible and robust platform includes viewing, archiving, management, workflow and distribution of images as well as an open architecture for core competency tool development.

Computer programs for application in Sports science, Physical Culture, among others. By Enrique R.P. Buendía Lozada. buendiaenr@gmail.com , Benemérita Universidad Autónoma de Puebla (BUAP), México. (Software without any warranty).

A simple, point of care, clinic decision support system (CDSS) Android app for Insulin infusion and hyperglycemia management in the ICU. The infusion protocol calculator is based on the updated "Yale Insulin Infusion Protocol" http://bit.ly/1DaVfUd and American Association of Clinical Endocrinologists (AACE) blood sugar targets. http://inpatient.aace.com/ . Source code requires Xamarin Studio & Android SDK to compile.

AUDocker is a GUI for AutoDock Vina.. helps in virtual screening of huge number of ligands continuously. Helps in resumption of work in accidental shutdowns..

PANDA is a comprehensive and flexib tool for quantitative proteomics data analysis, which is developed based on our solid foundations in quantitative proteomics for years. Several novelties have been implemented in it. First, we implement the advantage algorithms of LFQuant (Proteomics 2012, 12, (23-24), 3475-84) and SILVER (Bioinformatics 2014, 30, (4), 586-7) into PANDA. Second, we consider the state-of-art concept of quantification reliability in this quantitative workflow. On the levels of spectra, peptides and proteins, PANDA works out a few quantitative filters and new scores for quantification confidence. Third, PANDA is designed for processing proteomics big data in parallel.

WinBlast is a Windows graphical front-end for NCBI BLAST. It is written completely in C#, utilizing Microsoft’s latest .NET framework. WinBlast will run on any Windows machine that supports Microsoft .NET framework.

The Systems Biology Workbench(SBW) is a framework for application intercommunications. It uses a broker-based, distributed, message-passing architecture, supports many languages including Java, C++, Perl & Python, and runs under Linux,OSX & Win32. It comes with a large number of modules, encompassing the whole modeling cycle: creating computational models, simulating and analyzing them, visualizing the information, in order to improve the models. All using community standards, such as SED-ML, SBML and MIRIAM.

Latronix Regnum Arts - Open Source Faction is an open source and freeware developer for all sorts of goodies. Be it games or applications. This is the home for the Drug Turfs Game (A Drug Wars like game) and the Drug Turfs Library.

JAligner is an open source Java implementation of the dynamic programming algorithm Smith-Waterman with Gotoh's improvement for biological local pairwise sequence alignment with the affine gap penalty model.

A medical information system for Windows-based systems (95-XP/CE/PocketPC) based on Open Source platforms

The cancer Biomedical Informatics Grid being developed by the NCI is a virtual informatics infrastructure that connects data, research tools, and scientists. This project is developing extensions to MS Excel that allow users to access caBIG data-services.

Morpheus is a mass spectrometry–based proteomics database search algorithm designed from the ground up for high-resolution tandem mass spectra. We have discovered that for high-resolution MS/MS, simple spectrum preprocessing and scoring performs superior to more complex algorithms originally developed for low-resolution MS/MS, such as Sequest, Mascot, and OMSSA. Morpheus is also very fast—up to nearly 5 times faster than OMSSA for large human datasets. It is written in C# and is available open source under the permissive MIT License.

An assessmemt tool of sequence repeats for short read sequencing.

A C# implementation of LOGO which allows to reproduce many real world (complex) phenomena governed by local rules like traffic jams, gas diffusion, aggregation and percolation, ant systems and biological systems in general.

TraceViewer provides several functionalities needed by any biologist who wants to efficiently analyse his/her trace data.

A main aim of this project is to deliver an infrastructure for HL-7 v3 compilant messages exchange. This infrastructure should be based on existing real time queueing system such as Apache ActiveMQ. A product of this project does not include user interfa

.Net based tools for AnIML formatted data files

The major mechanism driving cellular differentiation and organism development is the regulation of gene expression. Cis-acting en-hancers and silencers appear to have key roles in regulating gene expression. Arabidopsis Motif Scanner was design to build gene networks by identifying the cis-regulatory elements position in the model plant Arabidopsis thaliana and by providing an easy interface to evaluate gene relations.

BRISC (BRISC Really IS Cool) is 1) a library for Haralick, Gabor and Markov image feature extraction from pulmonary nodule DICOM images and 2) a simple content-based image retrieval (CBIR) system for pulmonary nodule databases (ie. LIDC).

BigBang/Horizon is a proteomics data analysis pipeline with focus on the shotgun LC/MSMS workflow.

BioCSharp is an open-source project designed to provide a bioinformatics .NET framework for processing biological data. It will include objects for manipulating sequences, file parsers, DAS, database access and analysis and statistical routines.

BioSharp is an open source framework for processing biological data, based on BioJava.