Audience

Chemical engineers and researchers interested in a tool to predict thermodynamic properties of liquids accurately, facilitating efficient solvent selection and formulation design

About BIOVIA COSMOtherm

BIOVIA COSMOtherm is an advanced COSMO-RS implementation that combines quantum chemistry and thermodynamics to predict thermodynamic properties of liquids. It calculates the chemical potential of molecules in pure or mixed liquids across variable temperatures, enabling the prediction of properties such as solubility, partitioning, vapor pressure, and phase diagrams. Unlike other methods, COSMOtherm applies thermodynamically consistent equations to predict properties as functions of concentration and temperature. Key features include the ability to predict solubility of liquids, solids, and gases; activity coefficients; two-phase partitioning (e.g., LogP); phase behavior; vapor pressures; free energy of solvation; pKa; energy of transfer to liquid-liquid interfaces; micelle and membrane partitioning; and interfacial tension. COSMOtherm offers an easy-to-use graphical interface and a command-line version for seamless integration into existing workflows.

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Integrations

No integrations listed.

Ratings/Reviews - 1 User Review

Overall 5.0 / 5
ease 4.0 / 5
features 4.0 / 5
design 4.0 / 5
support 3.0 / 5
More Reviews Write a Review

Company Information

Dassault Systèmes
Founded: 1981
France
www.3ds.com/products/biovia/cosmo-rs/cosmotherm

Videos and Screen Captures

BIOVIA COSMOtherm Screenshot 1
BIOVIA COSMOtherm Screenshot 1 BIOVIA COSMOtherm Screenshot 2
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Product Details

Platforms Supported
Windows
Training
Documentation
Live Online
Webinars
In Person
Videos
Support
Phone Support
24/7 Live Support
Online

BIOVIA COSMOtherm Frequently Asked Questions

Q: What kinds of users and organization types does BIOVIA COSMOtherm work with?
Q: What languages does BIOVIA COSMOtherm support in their product?
Q: What kind of support options does BIOVIA COSMOtherm offer?
Q: What type of training does BIOVIA COSMOtherm provide?

BIOVIA COSMOtherm Product Features

Chemical

ISO Management
Traceability
Samples Tracking
Reporting & Statistics
Particle Tracking
Uncertainty Analysis
Certificates of Analysis
Inventory Management
Chemical Process Simulation
Computer-Assisted Structure Elucidation (CASE)

BIOVIA COSMOtherm Verified User Reviews

Write a Review
  • Ramakrishna K.
    Simulation & modelling specialist
    Used the software for: 2+ Years
    Frequency of Use: Daily
    User Role: User
    Company Size: 20,000 or More
    Design
    Ease
    Features
    Pricing
    Support
    Probability You Would Recommend?
    1 2 3 4 5 6 7 8 9 10

    "Predictive Power Unleashed: A Deep Dive into BIOVIA COSMOtherm"

    Posted 2025-10-28

    Pros: Accurate Property Prediction
    User-Friendly Interface
    Supports Sustainable Innovation
    Versatile Applications

    Cons: License Cost
    Steep Learning Curve
    Limited for Highly Complex Systems
    Computational Demands

    Overall: BIOVIA COSMOtherm delivers a powerful and reliable platform for predicting thermodynamic properties of chemical systems without experimental data. Its COSMO-RS-based modeling is impressively accurate for solubility, partitioning, and mixture behavior, making it a go-to tool for formulation scientists and process engineers. The interface is intuitive, and its integration with other BIOVIA tools enhances workflow efficiency. While it demands a solid understanding of physical chemistry and comes with a premium price tag, the value it offers in accelerating R&D and supporting green chemistry initiatives is undeniable

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